diff --git a/python-lxml.spec b/python-lxml.spec
index 59811e1..d29388a 100644
--- a/python-lxml.spec
+++ b/python-lxml.spec
@@ -14,6 +14,7 @@ Source:         %{pypi_source lxml}
 BuildRequires:  gcc
 BuildRequires:  libxml2-devel
 BuildRequires:  libxslt-devel
+BuildRequires:  python3-devel
 
 %global _description \
 lxml is a Pythonic, mature binding for the libxml2 and libxslt libraries. It\
@@ -25,9 +26,6 @@ XML Schema, XSLT, C14N and much more.
 
 %package -n     python3-lxml
 Summary:        %{summary}
-BuildRequires:  python3-devel
-BuildRequires:  python3-setuptools
-BuildRequires:  python3-Cython
 Suggests:       python3-lxml+cssselect
 Suggests:       python3-lxml+html5
 Suggests:       python3-lxml+htmlsoup
@@ -36,18 +34,25 @@ Suggests:       python3-lxml+htmlsoup
 
 Python 3 version.
 
-%python_extras_subpkg -n python3-lxml -i %{python3_sitearch}/lxml-*.egg-info cssselect html5 htmlsoup
+%pyproject_extras_subpkg -n python3-lxml cssselect html5 htmlsoup
 
 %prep
 %autosetup -n lxml-%{version} -p1
+
+%generate_buildrequires
+%pyproject_buildrequires -x source,cssselect,html5,htmlsoup
 # Remove pregenerated Cython C sources
-find -type f -name '*.c' -print -delete
+# We need to do this after %%pyproject_buildrequires because setup.py errors
+# without Cython and without the .c files.
+find -type f -name '*.c' -print -delete >&2
 
 %build
-env WITH_CYTHON=true %py3_build
+export WITH_CYTHON=true
+%pyproject_wheel
 
 %install
-%py3_install
+%pyproject_install
+%pyproject_save_files lxml
 
 %check
 # The tests assume inplace build, so we copy the built library to source-dir.
@@ -56,11 +61,9 @@ cp -a build/lib.%{python3_platform}-*/* src/
 # The options are: verbose, unit, functional
 %{python3} test.py -vuf
 
-%files -n python3-lxml
-%license LICENSES.txt doc/licenses/BSD.txt doc/licenses/elementtree.txt
+%files -n python3-lxml -f %{pyproject_files}
+%license doc/licenses/BSD.txt doc/licenses/elementtree.txt
 %doc README.rst src/lxml/isoschematron/resources/xsl/iso-schematron-xslt1/readme.txt
-%{python3_sitearch}/lxml/
-%{python3_sitearch}/lxml-*.egg-info/
 
 %changelog
 * Wed Aug 31 2022 Miro Hrončok <mhroncok@redhat.com> - 4.7.1-6