diff --git a/guile-configure.patch b/guile-configure.patch
new file mode 100644
index 0000000..e5b9436
--- /dev/null
+++ b/guile-configure.patch
@@ -0,0 +1,21 @@
+diff -Nrup a/m4/mathfunc.m4 b/m4/mathfunc.m4
+--- a/m4/mathfunc.m4	2016-12-14 17:03:33.000000000 -0700
++++ b/m4/mathfunc.m4	2020-01-06 19:48:46.684158282 -0700
+@@ -60,7 +60,7 @@ AC_DEFUN([gl_MATHFUNC],
+              #endif
+              #include <math.h>
+              $4
+-             $2 (*funcptr) $3 = ]func[;
++             __attribute__ ((used)) $2 (*funcptr) $3 = ]func[;
+              int i_ret;
+              float f_ret;
+              double d_ret;
+@@ -85,7 +85,7 @@ AC_DEFUN([gl_MATHFUNC],
+                #endif
+                #include <math.h>
+                $4
+-               $2 (*funcptr) $3 = ]func[;
++               __attribute__ ((used)) $2 (*funcptr) $3 = ]func[;
+                int i_ret;
+                float f_ret;
+                double d_ret;
diff --git a/guile22.spec b/guile22.spec
index 8b6b315..f68f6c9 100644
--- a/guile22.spec
+++ b/guile22.spec
@@ -7,7 +7,7 @@
 Summary: A GNU implementation of Scheme for application extensibility
 Name: guile22
 Version: 2.2.6
-Release: 2%{?dist}
+Release: 3%{?dist}
 Source: ftp://ftp.gnu.org/pub/gnu/guile/guile-%{version}.tar.gz
 URL: http://www.gnu.org/software/guile/
 License: LGPLv3+
@@ -20,6 +20,7 @@ Provides: bundled(gnulib)
 Patch1: guile-multilib.patch
 Patch3: guile-threadstest.patch
 Patch4: disable-out-of-memory-test.patch
+Patch5: guile-configure.patch
 
 %description
 GUILE (GNU's Ubiquitous Intelligent Language for Extension) is a library
@@ -49,9 +50,11 @@ install the guile package.
 %patch1 -p1 -b .multilib
 %patch3 -p1 -b .threadstest
 %patch4 -p1
+%patch5 -p1 -b .configure
 
 %build
 
+autoreconf -fiv
 %configure --disable-static --disable-error-on-warning --program-suffix=%{?mver}
 
 # Remove RPATH
@@ -168,6 +171,9 @@ fi
 
 
 %changelog
+* Fri Jan 17 2020 Jeff Law <law@redhat.com> - 2.2.6-3
+- Fix configure tests compromised by LTO
+
 * Thu Jul 25 2019 Fedora Release Engineering <releng@fedoraproject.org> - 2.2.6-2
 - Rebuilt for https://fedoraproject.org/wiki/Fedora_31_Mass_Rebuild