diff --git a/comps-fe6.xml.in b/comps-fe6.xml.in
index b9f3c7bf..8103b404 100644
--- a/comps-fe6.xml.in
+++ b/comps-fe6.xml.in
@@ -344,7 +344,9 @@
       <packagereq type="optional">paraview</packagereq>
       <packagereq type="optional">paw</packagereq>
       <packagereq type="optional">pcb</packagereq>
+      <packagereq type="optional">perl-bioperl</packagereq>
       <packagereq type="optional">plotutils</packagereq>
+      <packagereq type="optional">python-biopython</packagereq>
       <packagereq type="optional">qalculate-gtk</packagereq>
       <packagereq type="optional">qalculate-kde</packagereq>
       <packagereq type="optional">qcad</packagereq>
@@ -363,6 +365,7 @@
       <packagereq type="optional">veusz</packagereq>
       <packagereq type="optional">wcstools</packagereq>
       <packagereq type="optional">wgrib</packagereq>
+      <packagereq type="optional">wise2</packagereq>
       <packagereq type="optional">wvs-data</packagereq>
       <packagereq type="optional">wxMaxima</packagereq>
       <packagereq type="optional">xcircuit</packagereq>